MK-Ultra was a covert and illegal project of the CIA stretching over the course of the 1950's and 60's, involving human experimentation.
During "The Unusual Suspects", three MK-Ultra scientists were murdered by Red Flag assassins. Dr. Rosen has access to a set of files from the project, and a morphogene Red Flag agent attempts to infiltrate the office and destroy the files. All of these events imply that the DoD's current involvement in Alphas stems from the MK-Ultra experiments.
During the Cold War, to combat Communist espionage, the CIA developed numerous programs for alternative counter-tactics. Following rumors of mind-control and brainwashing techniques during the Korean War, Project MK-Ultra was born.
Following Freedom of Information declassification, the public knows of the following tactics explored by the project:
- Mind-altering substances, including LSD, barbituates, and amphetamines.
- Psychological attacks, including mind-altering practices such as sleep deprivation, isolation, hypnosis, and sensory overload.
Most notoriously, these experiments were done often without the subject's consent, and resulting in at least one death.
MK-Ultra's name comes from digraph MK, meaning that the project was sponsored by the agency's Technical Services Staff, followed by the word Ultra (which had previously been used to designate the most secret classification of World War II intelligence).